The NFL Week 1 schedule is loaded with high-profile NFL matchups and tight NFL spreads, including four battles between last season’s playoff teams and three divisional games. Jim Harbaugh will begin his Chargers coaching career on Sunday when Los Angeles hosts the Las Vegas Raiders in an AFC West matchup. The Chargers were forced to make salary cap concessions in the offseason, but they still have quarterback Justin Herbert and now have a coach who is consistently winning. Los Angeles is a three-point favorite in the Week 1 NFL odds, according to SportsLine Consensus. Who should you bet on in that matchup and which team should you favor when making your Week 1 NFL predictions? Before you make your Week 1 NFL picks, you should check out the NFL spread, over/under and moneyline predictions provided by SportsLine AI.
Built by SportsLine’s data science team using cutting-edge artificial intelligence and machine learning technology, AI predictions and AI ratings are generated for each game. AI predictions are determined by statistically learning from historical data for each team and quantitatively rating the strength of the opponent’s defense by assigning it a numerical value out of 100, called a Matchup Score.
Once a prediction is formulated, an AI rating is generated using the prediction, match score and market odds. For example, if a team has a weak defense, the prediction differs from the line and the odds are in your favour, you may see an A rating on an over bet.
Plus, SportsLine AI is SportsLine’s first fully automated prediction model, which is continually updated with the latest available data to help you find the biggest discrepancies in lines. Last season, SportsLine’s AI PickBot hit 1,674 4.5- and 5-star prop picks, a difference that anyone who’s used the tool can attest to.
In Week 1, AI PickBot evaluated the NFL odds and provided NFL predictions for all 16 games. Here you can see only the AI predictions for Week 1 NFL schedule.
Top NFL AI picks for Week 1
After analyzing all the games in Week 1, AI PickBot states the Broncos will cover a 5.5-point underdog against the Seahawks in a game that gets an A-rated pick. Denver went 5-12 in 2022 and started 1-5 in Sean Payton’s first year as coach, but the team clearly started to make gains in the second half of the season. The Broncos won five straight games midway through the season and ultimately finished the season with a respectable 8-9 record after a tough start.
But oddsmakers seem to be discounting the improvement shown by them significantly, setting the over/under for 2024 at six wins and making them the third-biggest underdog this week at 5.5 points in Week 1. Meanwhile, they seem to be overpricing a Seahawks team that started 5-2 but lost six of 10 games to miss the playoffs. While our AI pick bot is predicting a Seahawks win, the average final score of 21.86 to 20.34 puts the Broncos at +5.5, well within the margin of error. See Week 1 football predictions and football picks at SportsLine.
How to make Week 1 NFL picks
Additionally, AI PickBot generated eight A-rated picks for Week 1. Before you place any NFL bets for Week 1, you should check out AI PickBot’s analysis, which you can find exclusively at SportsLine.
Who will win and cover each NFL game in Week 1, and which A-rated picks should you bet on? Visit SportsLine now for the top NFL picks against the spread, over-under and money line, all powered by the all-new SportsLine AI PickBot, which hit the mark on 1,674 top-rated picks last season.
